Modeling and Visualization for Polymers, Surfaces and Biomolecules

Abstract

Our research emphasizes efficient algorithms and data structures for biomolecular modeling and visualization. The main research thrusts of this contract are: The computation of the topological, combinatorial and metric properties of the molecular structure of polymers and biomolecules based on weighted alpha shapes; The determination of similarities between two or more polymers or biomolecules based on geometric matching of the determined structural properties of the molecules; The development and graphical simulation of localized molecular docking strategies based on road map calculations on convolution surfaces of the interacting molecule structures and localized regions of the potential energy surfaces; The modeling, visualization and manipulation of the molecules together with their potential energy surfaces; The implementation of the above algorithms in an existing distributed (multi-user and multi-workstation) geometric software environment.

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Document Details

Document Type
Technical Report
Publication Date
Sep 02, 1997
Accession Number
ADA334687

Entities

People

  • Chandrajit L. Bajaj

Organizations

  • Princeton University

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Algorithms
  • Applied Mathematics
  • Biomolecules
  • Computations
  • Computer Graphics
  • Computer-Aided Design
  • Computers
  • Data Visualization
  • Electron Density
  • Energy
  • Geometry
  • Graphics
  • Mathematics
  • Molecular Structure
  • Molecules
  • Potential Energy
  • Visualizations

Readers

  • Computer Vision.
  • Database Systems and Applications
  • Oncology and Biomarker-Based Cancer Detection.