Does Subsequent Pregnancy Influence Breast Cancer Survival.
Abstract
This retrospective study is designed to provide an assessment of the risk of recurrence and death associated with pregnancy following primary and adjuvant breast cancer treatment. This major concern of young breast cancer patients who may have delayed childbearing. A collaborative record-linkage study is underway using the unique computerized records maintained by the Kaiser Permanente of Northern California. Through linkage of the cancer registry and hospitalization records, young breast cancer patients with a history of subsequent pregnancy have been identified. Medical record review is currently being conducted to collect data on epidemiologic risk factors and breast cancer stage, treatment and outcome factors. Four breast cancer cases without a history of pregnancy after breast cancer will be matched to each case by year and age at diagnosis, stage of disease, months of survival from diagnosis to first pregnancy outcome, and disease status during early pregnancy. Matched analyses methods will be used to compare disease free survival among cases with and without a history of subsequent pregnancy. Known and suspected prognostic factors will be controlled in the analysis. Among cases with a history of subsequent pregnancy, the effect of reproductive events prior to diagnosis, the months between diagnosis and first pregnancy, the number of subsequent pregnancies, and birth outcomes will be studied.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1997
- Accession Number
- ADA335852
Entities
People
- Ruby T. Senie
Organizations
- Memorial Sloan Kettering Cancer Center