Tumor-Specific Immunotherapy of Mammary Cancer

Abstract

For many patients with mammary cancer the primary tumor can be successfully treated by surgical removal, however the long-term prognosis is not favorable because of the high frequency of metastatic disease which is not treatable by current approaches. Our goal is to develop vaccination strategies to minimize metastatic disease. We postulate that an improvement in the generation of mammary carcinoma-specific CD4(+) T helper lymphocytes will facilitate development of CD8-mediated tumor immunity.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1997
Accession Number
ADA335941

Entities

People

  • Suzanne Ostrand-Rosenberg

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Antigens
  • Blood
  • Breast Cancer
  • Cells
  • Demographic Cohorts
  • Diseases And Disorders
  • Immunity
  • Immunization
  • Immunomodulation
  • Immunotherapy
  • Lymphatic System
  • Lymphocytes
  • Mammary Glands
  • Molecules
  • Neoplasms
  • T Lymphocytes
  • Therapy

Fields of Study

  • Medicine

Readers

  • Molecular Genetics
  • Molecular and genetic basis of cancer.
  • Oncology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech