Biochemistry and Chemotherapy of Malaria and Leishmaniasis.
Abstract
Malaria is the world's most ravaging infectious disease. It is rampant throughout much of the tropics and some of the temperate areas of the world. It threatens a third of the world's population, presently afflicting hundreds of millions of people, causing several million deaths annually and possibly generating as many as 92 million new clinical cases each year. The socioeconomic drain of the disease is enormous. Resurgence of this pestilence during the past 20 years due to global warming, drug resistance, and other factors has prompted increased research efforts in the production of an effective vaccine. In the interim, there must be a reliance on chemotherapy for prevention and treatment of the disease. The current research addressed the need to develop a broad-spectrum antimalarial. Research efforts focused on the propagation of malarial Parasites in vitro for the purpose of studying the unique biochemistry of the parasite with the goal of chemotherapeutic exploitation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1997
- Accession Number
- ADA336400
Entities
People
- Linda Nolan
Organizations
- University of Massachusetts Amherst