The Molecular Epidemiology of Breast Cancer: Risk From Environmental Exposures and Genetic Susceptibility

Abstract

This report includes results from a case-control study examining the relation of serum levels of DDE, hexachlorbenzene (HCB), and poly chlorinated biphenyls (PCBs) to risk of postmenopausal breast cancer. The study sample included 154 primary, incident, histologically confirmed, breast cancer cases and 192 community controls. In the entire sample there was no evidence of an adverse effect associated with serum levels of DDE, HCB, and several PCB exposure measures: total PCBs, total number of detected PCB congener peaks, and PCB congener groups. We consistently observed effect modification by history of lactation with respect to all exposures.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1997
Accession Number
ADA337489

Entities

People

  • Jo L Freudenheim
  • Kirsten Moysich

Organizations

  • University at Buffalo

Tags

DTIC Thesaurus Topics

  • Biphenyl
  • Breast Cancer
  • Cancer
  • Data Science
  • Detection
  • Diseases And Disorders
  • Environmental Exposure
  • Epidemiology
  • Factor Analysis
  • Health
  • Information Science
  • Materials
  • Measurement
  • Medical Personnel
  • Neoplasms
  • New York
  • Polychlorinated Biphenyls

Readers

  • Aviation Safety Risk Assessment.
  • Groundwater Contamination Remediation.
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation