Effects of Human Pregnancy on Responses to Exercise Above and Below the Ventilatory Anaerobic Threshold.

Abstract

The purpose of this contract is to study the effects of healthy human pregnancy on cardiac autonomic function (Study #1), oxygen uptake kinetics (Study #2), and acid-base regulation (Study #3) at rest and during upright cycling at intensities above and below the ventilatory anaerobic threshold (T(vent)). Study #1 is currently in progress and results to date support our hypotheses that cardiac parasympathetic nervous system activity is blunted in the resting state and that sympathetic activity is reduced during strenuous exercise above T(vent) in late gestation. Technical aspects of the study and the testing protocol have been finalized for Study #2 and data collection will begin in January 1998. Study #3 is essentially complete and supports the concept that arterialized plasma H+ is lower in the pregnant vs. nonpregnant state. However, changes in H+ induced by standardized strenuous exercise are comparable in the pregnant vs. nonpregnant state. Nonpregnant subjects may have greater reductions in the strong ion difference (SID) in response to exercise above (T(vent)), but this is compensated by a greater respiratory response and a reduced arterial plasma carbon dioxide tension. Our results to date support the hypothesis that healthy physically active women can safely adapt to short bouts of strenuous exercise in late gestation.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1997
Accession Number
ADA337800

Entities

People

  • Larry A. Wolfe

Organizations

  • Queen's University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acid-Base Equilibrium
  • Acid-Base Imbalance
  • Blood
  • Blood Proteins
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Chemical Synthesis
  • Chemistry
  • Electrolytes
  • Health Services
  • Heart Rate
  • Liquid Chromatography
  • Medical Personnel
  • Pregnancy Complications
  • Test Methods
  • Vascular Diseases

Readers

  • Aquatic Ecology
  • Cardiovascular Physiology
  • Systems Analysis and Design