Statistical Genetics Methods for Localizing Multiple Breast Cancer Genes.

Abstract

While breast cancer in many families is due to the known breast cancer genes, there is still a sizable proportion of families that do not show linkage to these known genes. Thus, it is important that other genetic loci responsible for these cases be investigated. The past year was mostly spent on developing theory for estimating linkage disequilibrium between a generalized mendelian locus and a nearby marker locus (Task 4). Work is progressing satisfactorily and results will be implemented in a computer program. A manuscript will be written in the next funding period.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1997
Accession Number
ADA337861

Entities

People

  • Jurg Ott

Organizations

  • Columbia University

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Cells
  • Computer Programs
  • Computers
  • Diseases And Disorders
  • Dna Sequence Analysis
  • Genetics
  • Health Services
  • Hereditary Diseases
  • Kidney Diseases
  • Medical Personnel
  • Neoplasms
  • New York
  • Skin Diseases
  • Universities

Fields of Study

  • Mathematics

Readers

  • Molecular and genetic basis of cancer.
  • Theoretical Analysis.

Technology Areas

  • Biotechnology