Cell Regulation by a Novel Estrogen Regulated Gene
Abstract
This report describes the work conducted in the first year of a two year IDEA. Our original proposal was funded to study a human estrogen regulated transcript, HEM45, that encodes a novel protein of 181 amino-acid residues (M, 20,300). The HEM45 protein has similarity to the bracket fungus protein FRTl that can cause fruiting-body production and to a Xenopus product, XPMC2, that affects cell-cycle control. These similarities suggest that HEM45 has a role in mediating the estrogen action control of cellular proliferation and differentiation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1997
- Accession Number
- ADA338782
Entities
People
- Brian T. Pentacost