Brain-Derived Neurotrophic Factor (BDNF) and Traumatic Brain Injury (Head and Spinal)

Abstract

The long term objective of this study is to improve functional outcome following traumatic brain injury (TBI) by enhancing mechanisms which are neuroprotective. This study investigates the role of neurotrophic factors in attenuating neuronal injury after brain trauma. Neurotrophic factors are a family of structurally related polypeptides which have been shown to play a critical role during neuronal development and appear to mediate a protective response to trauma and disease in mature animals.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1998
Accession Number
ADA339353

Entities

People

  • Ramona R. Hicks

Organizations

  • University of Kentucky

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Brain
  • Brain Injuries
  • Cell Physiological Processes
  • Central Nervous System
  • Chemistry
  • Diseases And Disorders
  • Epidermis
  • Films
  • Gene Expression
  • Growth Factors
  • Laboratory Animals
  • Mrna
  • Nervous System
  • Neurons
  • Neurosciences
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.