The Role of Apoptosis in Hypoxie Endothelial Cell Injury

Abstract

The objective of this report is to investigate the regulation of programmed cell death (apoptosis) in hypoxia resistant endothelial cells and hypoxia sensitive hepatoma cells. We will examine the cyto- protective role of Bcl-2 homologues in endothelial cells. Likewise, we will examine the ability of ICE and the ICE-like protease CPP32/YAMA to produce apoptosis.

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Document Details

Document Type
Technical Report
Publication Date
Feb 24, 1998
Accession Number
ADA340333

Entities

People

  • Robert K. Winn

Organizations

  • University of Washington

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Anatomy
  • Antisense Elements (Genetics)
  • Apoptosis
  • Biological Sciences
  • Cell Count
  • Cell Line
  • Cell Physiological Processes
  • Cell Physiology
  • Cells
  • Controlled Atmospheres
  • Electrophoresis
  • Endothelial Cells
  • Environment
  • Gel Electrophoresis
  • Military Research
  • Programmed Cell Death

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Immunology