Characterization of asgC a Gene Required for Cell-Cell Signaling Early Development of Myxococcus Xanthus

Abstract

Myxococcus xanthus is a soil bacterium that forms spore-filled fruiting bodies in response to nutrient limitation coupled with high cell density. Extracellular A-signal, which is composed of amino acids and peptides, is produced during early development and is thought to function as a cell density signal. The asgC gene is one of three known regulatory genes that are required for A-signal production. The asgA and asgB genes encode a signaling kinase and a putative transcription factor, respectively. The longterm goal of this project was to understand the role of asgC in A-signal production. To this end, the DNA sequence of asgC and the only known asgC mutant allele, asgC767, was determined.

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Document Details

Document Type
Technical Report
Publication Date
Mar 18, 1998
Accession Number
ADA344287

Entities

People

  • Lynda S. Plamann

Organizations

  • Texas A&M University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Anti-Bacterial Agents
  • Bacteria
  • Cell Physiological Processes
  • Cellular Structures
  • Chemistry
  • Dna Sequence Analysis
  • Escherichia Coli
  • Genetic Code
  • Genetics
  • Gram-Negative Bacteria
  • Health Services
  • Medical Personnel
  • Microbiology
  • Molecules
  • Proteins
  • Transcription Factors

Fields of Study

  • Biology

Readers

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  • Molecular Biology and Genetics