2-D and 3-D Digital Analysis of Breast Calcifications: A Technique to Improve Mammographic Specificity.
Abstract
Breast calcifications detected mammographically and considered indeterminate or suspicious, account for 50% of biopsies for mammographically detected nonpalpable lesions. The positive predictive value (PPV) of film screen mammography (FSMAM) in determining the malignant nature of calcifications is also low (approximately 30%) (Conant, et al, 1994) (Homer, 1992). We have developed a readily implementable technology that we believe will reduce the number of false positive breast biopsies of calcifications. Our technique of combining two-dimensional (2-D) and novel three-dimensional digital mammographic (3-D DMAM) analysis of breast calcifications allows the analysis of the 3-D morphology of individual calcifications as well as the 3-D spacial orientation of a cluster of calcifications in breast tissue.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1997
- Accession Number
- ADA348665
Entities
People
- Emily F. Conant
Organizations
- Thomas Jefferson University