Marine Viral Pathogens.

Abstract

The research funded by this award, sponsored investigations on novel marine viruses that were isolated in British Columbia coastal waters and the Gulf of Mexico. It was a continuation of Grant NOOOl4-92-J-l676 awarded at The University of Texas. The results included the isolation of a viral pathogen that infects a eukaryotic toxin-producing phytoplankton. The phytoplankton that is infected has been responsible for extensive fish kills in North American and Asia. The ultimate goal is to use these and other viral isolates as vectors for transforming and studying genetics in eukaryotic microalgae. As part of the research an unknown viral pathogen that infects microzooplankton has begun to be characterized. Ultimately, this research may lead to the development of in situ PCR-based methods to detect the presence of viral genes within infected cells, and for detection of novel and rare virus types in seawater. This will allow us to more effectively screen for the presence of potential lysogens, as well as allow us to determine the presence of infected cells in natural populations. We have also continued work on the development of fluorescently labeled virus technology as a tool to localize and isolate viral receptors on cell surfaces.

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Document Details

Document Type
Technical Report
Publication Date
May 13, 1998
Accession Number
ADA348949

Entities

People

  • Curtis Suttle

Organizations

  • University of British Columbia

Tags

Communities of Interest

  • Weapons Technologies

DTIC Thesaurus Topics

  • Bacteria
  • British Columbia
  • Cyanobacteria
  • Dna Viruses
  • Genetics
  • Microbial Genetics
  • Microbiology
  • Microorganisms
  • Oceanography
  • Pathogenic Bacteria
  • Phycodnaviridae
  • Phytoplankton
  • Radiation
  • Sequence Analysis
  • Solar Radiation
  • Universities
  • Viruses

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Marine Ecotoxicology
  • Microbial Pathology

Technology Areas

  • Biotechnology