The Regulation of Gene Expression in Cnidarian-Algal Associations.

Abstract

We have characterized genes encoding heat shock proteins and proteins of the ubiquitin system. Constitutive forms of the HSP60 and 70 families of heat shock proteins and an inducible form of HSP60 occur in symbiotic and aposymbiotic Aiptasia pallida. We have constructed cDNA libraries from aposymbiotic A. pallida and symbiotic A. pallida and Anthopleura eligantissima. We have a complete sequence for A. pallida HSP60. We have completed the comparison of protein profiles of A. eligantissima (see J. Exp Biol. 1996, 199:883-892) and have identified three symbiosis-specific proteins. One is carbonic anhydrase with an apparent molecular weight of 31 kDa and a pI of 6.3. We have obtained N-terminal sequence for second protein; it has an apparent molecular weight of 32 kDa and a pI of 7,9. It does not align with any sequences in the GenBank data base. A third symbiosis-specific protein, having an apparent weight of 30 kD and a pI of 5.6, crossreacts with a monoclonal anti-HSP70 antibody. The synthesis of this protein is enhanced in animals subjected to elevated temperatures and in animals maintained in the dark. Further investigations of these proteins are underway by Dr. Virginia Weis at Oregon State University.

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Document Details

Document Type
Technical Report
Publication Date
Jul 13, 1998
Accession Number
ADA349126

Entities

People

  • R. P. Levine

Organizations

  • Stanford University

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Animals
  • Antibodies
  • Cnidarians
  • Databases
  • Gel Electrophoresis
  • Gene Expression
  • Genetic Structures
  • Immune Serums
  • Military Research
  • Molecular Weight
  • Peptides
  • Proteins
  • Sequences
  • Technical Information Centers
  • Thermal Stresses
  • Virginia

Fields of Study

  • Biology

Readers

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