Studies of Monolayers of Cyclodextrin and Flavin Derivatives

Abstract

The goal of the research program is to develop the surface chemistry applications of cyclodextrins and flavins in a selected number of areas and is a combined effort of organic synthesis and physical measurements. A principle goal is to form self-assembled monolayers (SAMs) of sulfide modified cyclodextrins and evaluate their use in modifying substrates for surface-enhanced Raman spectroscopy in order to improve the sensitivity and selectivity of SERS for the application of environmental sensing. Another goal being pursued is to form SAMs of immobilized artificial flavoenzymes, consisting of a flavin group on the secondary side of the cyclodextrin cavity and methylsulfides on the primary side, and to evaluate the electrochemical and electrocatalytic behavior of these films. In relation to this goal, SAMs of flavin-sulfide derivatives are being prepared and their structure and electrochemical behavior studied. Amphiphilic flavins are being studied in mixed micelles and incorporated into Langmuir-Blodgett films.

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Document Details

Document Type
Technical Report
Publication Date
Jul 13, 1998
Accession Number
ADA349544

Entities

People

  • Keith J. Stine

Tags

DTIC Thesaurus Topics

  • Analytical Chemistry
  • Chemical Synthesis
  • Chemistry
  • Electron Transfer
  • Electronic Mail
  • Electrons
  • Field Emission
  • Films
  • Langmuir Blodgett Films
  • Minority Groups
  • Molecules
  • Monomolecular Films
  • Organic Chemistry
  • Raman Spectroscopy
  • Self Assembled Monolayers
  • Spectroscopy
  • Surface Chemistry

Fields of Study

  • Chemistry

Readers

  • Electrochemical Surface Science
  • Systems Analysis and Design
  • Thin Film Deposition Science.