Computer-Aided Classification of Malignant and Benign Lesions on Mammograms

Abstract

The purpose of this project is to develop computerized classification methods for mammographic abnormalities which will aid radiologists in deciding whether a patient should be biopsied. The regions of interest (ROIs) will be identified by radiologists, and the features to be used in classification will be computer-extracted image features. In the second year of our project, we have made progress in all five major objectives of the proposal. We have digitized over 600 new films for computerized analysis. We have investigated new segmentation and morphological feature extraction methods for classification of mammographic masses. We have investigated a new high-sensitivity training algorithm for artificial network, and designed a new hierarchical classifier for improved separation between malignant and benign cases. The mass classification algorithm that was developed in the first year of the project was evaluated with six radiologists in an observer study. The results of the observer study indicate that their classification accuracy was significantly improved when they were aided by our computer classification scores. Finally, using an artificial neural network classifier, texture features were evaluated for classification of 86 ROIs containing microcalcification clusters.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1998
Accession Number
ADA350905

Entities

People

  • Berkman Sahiner

Organizations

  • University of Michigan

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Algorithms
  • Artificial Intelligence
  • Artificial Intelligence Software
  • Biomedical Research
  • Computer Vision
  • Computers
  • Data Sets
  • Extraction
  • Feature Extraction
  • Films
  • Machine Learning
  • Materials
  • Neural Networks
  • Physicians
  • Sensitivity
  • Training

Fields of Study

  • Medicine

Readers

  • Computer Vision.
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • AI & ML
  • AI & ML - Neural Networks