A Study of the Endogenous Control of Neuroinflammation, A Leading Cause of Morbidity from Traumatic Brain Injury

Abstract

Neurotrauma constitutes 50% of combat related casualties. Among survivors, secondary injury contributes more to functional compromise than the primary traumatic event. A leading component of secondary injury is inflammation. Anti inflammatory therapy has not been exploited for central nervous system (CNS) injury because neuroinflammation is poorly understood. In this work, we provide the first in vivo demonstration of neuroinflammatory control.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1998
Accession Number
ADA352057

Entities

People

  • Geoffrey S. Ling

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Blood
  • Brain Injuries
  • Cells
  • Death
  • Diseases And Disorders
  • Health Services
  • Hematologic Diseases
  • Leukocytes
  • Medical Personnel
  • Proteins
  • Therapy

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.