Laser Spin-Exchange Polarized 3He and 129Xe for Diagnostics of Gas-Permeable Media with Nuclear Magnetic Resonance Imaging

Abstract

This work involves the development of a new implementation of magnetic resonance imaging using laser-polarized noble gases. Lasers are used to enhance the MR signal from noble gases such as 3He and 129Xe, making them easily observable in a conventional MRI scanner. Initial experiments have already yielded spectacular magnetic resonance images of the lungs of laboratory animals, and recently the first images of a human subject have been produced. This technology should provide functional information that can be important in evaluating and treating pulmonary embolisms, emphysema, asthma, lung cancer and a wide variety of respiratory problems. Lung function is an important concern for the DoD in many areas, including lung function of aviators at high altitudes, deep sea divers, and chemical warfare environments.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1996
Accession Number
ADA353888

Entities

People

  • William Happer

Organizations

  • Princeton University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alkali Metals
  • Animals
  • Embolism And Thrombosis
  • High Altitude
  • High Pressure
  • Laboratory Animals
  • Laser Arrays
  • Laser Diodes
  • Lasers
  • Magnetic Fields
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Medical Personnel
  • Noble Gases
  • Nuclear Magnetic Resonance
  • Nuclear Spins
  • Resonance

Fields of Study

  • Physics

Readers

  • Cardiovascular Physiology
  • Image Processing and Computer Vision.
  • Quantum spin resonance or Electron Paramagnetic Resonance spectroscopy.

Technology Areas

  • Directed Energy
  • Directed Energy - Lasers