Fluorescence Lifetime Imaging for Breast Cancer Detection and Diagnosis
Abstract
In this exploratory research program, the use of fluorescent contrast agents for detection and diagnosis of sub-surface diseased tissues is demonstrated. Using Newton-Raphson inversion techniques, we demonstrated the ability to map fluorescence lifetime and quantum efficiency from frequency-domain measurements of photon migration using synthetic data sets. Multi-pixel instrumentation for generation of actual data sets was constructed and is planned to validate the approach of fluorescence lifetime imaging of breast disease using optical contrast agents.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1998
- Accession Number
- ADA357315
Entities
People
- Eva M. Sevick-muraca
Organizations
- Purdue Research Foundation