Comparative Genomic Hybridization Onto Dense Arrays of DNA Clones: Development and Application to Breast Cancer Genomes.
Abstract
The work under the final portion of U.S. Army grant DAMD17-96-1-6165 focused on the technical aspects to produce high density arrays in automated fashion. A printing robot was constructed that used a capillary print head developed in the first year of this grant. This printer was shown to produce arrays that performed as well as our previous hand-spotted arrays. Much less target DNA is necessary, permitting faster, cheaper automated clone purification procedures, such as the Autogen machine. Finally, I developed an improved narrow bore capillary print head capable of printing arrays of densities 104/cm2.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1998
- Accession Number
- ADA357608
Entities
People
- Steven M. Clark
Organizations
- University of California, San Francisco