Hematologic Changes During and Following Cardiopulmonary Bypass and Their Relationship to Non-Surgical Blood Loss. 1. Platelet Function and the Bleeding Time.

Abstract

The changes in platelet parameters and the bleeding time during and following cardiopulmonary bypass (CPB) and their relationships to non-surgical blood loss following the administration of protamine were investigated in 85 adult male patients undergoing coronary artery and valvular heart surgery. The bleeding time was determined preoperatively, and 2, 24, 48, and 72 hours postoperatively. The blood shed from the site of the bleeding time determination was assayed for throbboxane B2 (shed blood TxB2) and 6-ketoprostaglandin F-1-alpha (shed blood 6-keto) levels.

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Document Details

Document Type
Technical Report
Publication Date
Jul 31, 1990
Accession Number
ADA360145

Entities

People

  • Gina Ragno
  • Miguel Josa
  • Samar Assousa
  • Shukri F. Khuri
  • Trevoc C. Axford

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood
  • Blood Transfusions
  • Cardiovascular Surgery
  • Data Analysis
  • Department Of Veterans Affairs
  • Health Services
  • Hemostasis
  • Information Science
  • Linear Regression Analysis
  • Measurement
  • Military Research
  • Platelet Activation
  • Regression Analysis
  • Surgery
  • United States
  • United States Government

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology