Effects of Syngeneic Fresh and Liquid Preserved Red Blood Cells on Primary and Metastatic Growth of the Lewis Lung Carcinoma in Mice.

Abstract

This Study examined the effects of transfusion of fresh and liquid pr served syngeneic red blood cells on the primary and metastatic growth of the Lewis Lung Carcinoma in mice. Trans fusions of nonviable syngeneic red blood cells enhanced the growth of metastatic tumors in four out of the seven experiments. The conflicting results observed may have been due to the differences in the virulence of the tumor cells associated with the number of tumor transfers from-one mouse to another for the various experiments.

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Document Details

Document Type
Technical Report
Publication Date
Aug 19, 1993
Accession Number
ADA360153

Entities

People

  • C. R. Valeri
  • Hong Qu
  • John Dittmer
  • Linda E. Pivacek
  • Toshio Ichikura

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Blood Transfusions
  • Cancer
  • Carcinoma
  • Cardiovascular System
  • Cell Count
  • Cells
  • Dermatologic Agents
  • Diameters
  • Digestive System Processes
  • Immune System
  • Lymphatic System
  • Lymphocytes
  • Neoplasms
  • Radioactivity
  • Viability

Readers

  • Immunology
  • Molecular and genetic basis of cancer.