Increased Platelet Reactivity and Circulating Monocyte-Platelet Aggregates in Patients with Stable Coronary Artery Disease
Abstract
Platelet-dependent thrombosis and leukocyte infiltration into the vessel wall are characteristic cellular events seen in atherosclerosis. We examined whether patients with stable coronary artery disease (CAD) have increased platelet reactivity- and an enhanced propensity to form monocyte-platelet aggregates. - As determined by whole blood flow cytometry, patients with stable coronary artery disease have circulating activated platelets, circulating monocyte-platelet aggregates, increased platelet reactivity, and an increased propensity to form monocyte-platelet aggregates.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1996
- Accession Number
- ADA360166
Entities
People
- C. R. Valeri
- M. I. Furman
- M. L. Borbonw
- R. C. Becker
- S. E. Benoit