Clinical Safety of Dimethylsulfoxide (DMSO) as a Platelet Cryopreservative
Abstract
Nine healthy volunteers were each transfused with 30 ml of a washed previously frozen platelet suspension containing an average of 119 mg + - 54 S.D. residual DMSO. Three of the nine volunteers had not been previously transfused with DMSO platelets. Blood samples were collected for laboratory examination prior to transfusion, 1 hour, 2 hours, 24 hours, 3 to 7 days, and >7 days following transfusion. During 1987 nine volunteers transfused prior to 1987 returned for follow-up blood examinations; one of the nine also had an eye examination. During 1988 one volunteer transfused prior to 1988 returned for blood and eye examinations. There was no evidence of lenticular opacities observed in the eye examinations in 1987 and 1988.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1996
- Accession Number
- ADA360202
Entities
People
- C. R. Valeri