An Experience Using Postoperatively Collected Orthopaedic Nonwashed Filtered Shed Blood Obtained from Knees and Hips as a Source of Autologous Red Blood Cells
Abstract
This study was done to evaluate the in vitro quality of shed blood collected with or without acid-citrate-dextrose (ACD, NIH, Formula A) from the knee and hip within the 12-hour period following orthopaedic surgery. The quality of the 450 to 500 ml of shed blood collected with or without ACD was similar whether collected within 4 hours after surgery, between 4 and 6 hours after surgery, or more than 6 hours after surgery: the hemoglobin concentration was 11.5 gm%, hematocrit 34 V%, WBC count 4,800/mm(exp 3), plasma hemoglobin 250 mg%, fibrinogen level less than 20 mg%, factor V clotting protein less than 10% of normal, factor VIII clotting protein 45% of normal, anti-thrombin III level 45% of normal, plasminogen level 55% of normal, protein C level 100% of normal, and fibrin degradation products of 1,000 micrograms/mil. A total of 205 units of nonwashed shed blood were reinfused into 153 patients and clinical responses were observed. Hematologic and plasma protein levels were measured in 126 patients who received 170 units of nonwashed shed blood. Measurements were made prior to and 1 hour and 24 hours after the transfusion of 1 to 4 units of shed blood which was filtered but not washed prior to transfusion.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 16, 1990
- Accession Number
- ADA360214
Entities
People
- C. R. Valeri
- E. M. Keating
- Merrill A. Ritter
- Philip M. Faris
Organizations
- Boston University