Myocardial Infarction and Transfusion Requirements in Transfusion Dependent Anemic Patients
Abstract
The influence of myocardial infarction (MI) on the transfusion requirements of transfusion dependent patients has not been previously studied. We studied thirty frequently transfused patients on long-term hemodialysis and a similar number of age and sex matched patients who were infrequently transfused to ascertain the influence of MI on transfusion requirements. Patients with evidence of previous MI on EKG in the transfused and control groups were similar (40% and 36% respectively), which indicated that the presence of a prior MI did not of itself determine which long term dialysis patients were more likely to be transfusion dependent. In frequently transfused patients with MI the principal influence of MI was that there was the difference in the hemoglobin level (transfusion trigger) at which these patients were transfused was observed in comparison to those without MI (8.3 +/- 1.5 g/dl vs. 6.9 +/- 1 g/dl, p 0.01). Patients with MI require a higher level of hemoglobin than patients without MI and these patients should be carefully monitored for the adequacy of their hemoglobin level when they are transfusion dependent. Further studies will be needed to elucidate the mechanism responsible for the higher required hemoglobin level in frequently transfused patients with MI.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 15, 1990
- Accession Number
- ADA360239
Entities
People
- C. R. Valeri
- James P. Crowley
- Joseph Chazan
Organizations
- Boston University