The Effects of the Infusion of Stroma-Free Hemoglobin Into Dogs with Spleens

Abstract

Stroma-free hemoglobin (SFH) solutions may be useful as a resuscitative fluid having oxygen-transporting capacity. SFH modified by intramolecular and intermolecular crosslinking has been shown to have longer vascular retention times. Potential problems with the infusion of SFH include vasoconstrictor effects, renal toxicity, increased methemoglobin levels, and disseminated intravascular coagulation.

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Document Details

Document Type
Technical Report
Publication Date
Jun 03, 1991
Accession Number
ADA360255

Entities

People

  • Alan C. Gray
  • C. R. Valeri
  • George Cassidy
  • Linda E. Pivacek

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Blood Cells
  • Blood Coagulation Factors
  • Blood Gases
  • Blood Volume
  • Cell Count
  • Classification
  • Clearances
  • Fluids
  • Hematocrit
  • Hematologic Diseases
  • Hemoglobin
  • Measurement
  • Methemoglobin
  • Security
  • Veins

Fields of Study

  • Chemistry
  • Mathematics
  • Medicine

Readers

  • Cardiovascular Physiology
  • Polymer Science and Technology