The Volume of Blood Shed During the Bleeding Time Correlates with the Peripheral Venous Hematocrit
Abstract
The relation between the bleeding time, the peripheral venous hematocrit and the amount of blood shed at the template bleeding time site has not been previously defined. We studied this relation in 227 individuals: 26 were patients with ITP, 137 were patients with a variety of other bleeding disorders, and 64 were normal subjects. The bleeding time for the normal group was 7.1 +/- 1.2 minutes, and the amount of shed blood was 136.4 +/- 47.2 microliters. In patients with ITP the bleeding time was 14.0 +/- 4.1 minutes and the shed blood was 508.1 +/- 387 microliters. In the group of individuals with other miscellaneous bleeding disorders, the mean bleeding time was 9.0 + 3.5 minutes and the amount of shed blood was 224.7 +/- 184 microliters. Bleeding times from all of the normal and abnormal individuals showed a correlation of 0.75, p < 0.001 with respect to the amount of shed blood on the filter paper and a correlation of 0.28, p < 001 with respect to the peripheral venous hematocrit. There was also a significant correlation between the bleeding time and the platelet count (r = 0.43, p < 0.05), in patients with ITP. This study demonstrates that the volume of blood shed at the bleeding time site correlates with the peripheral venous hematocrit, and emphasizes the contribution of the hematocrit to primary hemostasis in normal subjects and patients with bleeding disorders.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 11, 1997
- Accession Number
- ADA360326
Entities
People
- C. R. Valeri
- J. B. Metzger
- J. P. Crowley