Support of the Center for Prostate Disease Research at the Walter Reed Army Institute of Research..

Abstract

The congressionally mandated Center for Prostate Disease Research (CPDR) was established in 1992 as a program to study prostate cancer and prostatic disease in the U.S. military health care system. Initial funding through the Walter Reed Army Institute of Research (WRAIR) was used to establish a comprehensive laboratory for the molecular biologic study of genetic and cellular alterations that may contribute to the pathogenesis of prostate cancer. Through an MOU, the laboratory was established at the Uniformed Services University of the Health Sciences (USUHS) and contracted to the Henry M. Jackson Foundation for the Advancement of Military Medicine (HMJF). During the ensuing five years, HMJF scientists and technicians worked with the PI and other government and military members at USUHS to conduct numerous studies. The following report summarizes progress in the areas of genetic alterations and novel gene discovery, functional genetics, androgen mechanisms, prostate cell biology, and preclinical models of gene therapy. Through funding from USAMRMC and other private and public sources, the CPDR program continues to expand and is enhancing the understanding of the molecular mechanisms of prostate tumorigenesis.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1998
Accession Number
ADA360393

Entities

People

  • Judd Moul

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Cell Biology
  • Cell Physiological Processes
  • Cells
  • Dna Microarrays
  • Epithelial Cells
  • Gene Therapy
  • Genetic Code
  • Genetic Structures
  • Genetics
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Prostate Cancer
  • Vaccines

Fields of Study

  • Medicine

Readers

  • Molecular and genetic basis of cancer.
  • Naval Engineering and Maritime Security
  • Research Science/Academic Research

Technology Areas

  • Biotechnology