Extension of Post-Than-Wash Storage of Glycerol-Frozen Red Blood Cells at 4 C In 0.9% Sodium Chloride-0.1% Glucose Solution.
Abstract
The FDA has approved the protocol by which red blood cells can be frozen with 40% W/V glycerol, stored at -80 deg C, deglycerolized using the Naval Blood Research Laboratory (NBRL) Standard Operating Procedure for non-rejuvenated red blood cells, and stored in a 0.9% sodium chloride-0.2% glucose solution for 24 hours at 4 deg C. The Department of Defense (DoD) has approved this method for the deployment of frozen blood banks where glycerol-frozen red blood cells are stored at -8 deg C for 10 years. The NBRL has collected the enclosed data to support the extension of the postthaw storage period from 24 hours to 5 days. We are requesting the extension of the post-thaw-wash storage period for red blood cells from 24 hours to 5 days in view of the fact that the FDA has approved the storage of platelets at 22 deg C for 5 days, and the potential for contamination is similar for both.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 06, 1994
- Accession Number
- ADA360423
Entities
People
- C. R. Valeri
Organizations
- Boston University