Breast Cancer Tissue Repository.
Abstract
The Breast Tissue Respository at Duke University has completed its fourth1 year of flinding. This resource was designed to: 1.)provide freshly frozen tumor tissue from primary and metastatic sites (lymph nodes) for exploratory research, 2.) collect serum and plasma from patients and controls, and 3.) collect white blood cells from patients and controls. During the past year, we collected tumor tissue from 86 patients, 128 patients donated pre-operative blood samples, and 10 specimens were collected in a sterile fashion for special studies. We provided investigators at Duke and collaborating centers with more than 300 samples of frozen breast tumors. In each case, the quality of the tissue was determined by frozen section analysis and macrodissection done to enhance the fraction of the tissue specimen which contained malignancy. Blood samples were distributed to investigators at Duke and sent to collaborators in other institutions. We have applied for administrative continuation (without funding) to continue the process of serial blood collection from patients already consented and who have already provided a first blood sample. As a partial indication of the success of this bank, we competed for and received a Planning Grant in Breast Cancer from the NCI in 1994. A SPORE in Breast Cancer was awarded in 1995 and a Cancer Genetics Network grant started in 1998.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1998
- Accession Number
- ADA360856
Entities
People
- J. D. Iglehart
Organizations
- Duke University