Synthesis of Bis(8-aminoquinoline)-substituted Tetraazacrown Ethers by a Reductive Amination Process
Abstract
Four new tetraazacrown ethers containing two 8-aminoquinoline side arms were prepared first by reductive amination of 8-nitroquinolin-2-carboxaldehyde with the appropriate tetraazacrown ether containing two NH functions (see our Technical Report No. 4). The resulting bis(8-nitro-2-quinolinylmethyl)-substituted tetraazacrown ethers were reduced by iron and HCl to form the N,N'-bis(8-amino-2-quinolinylmethyl)-substituted tetraazacrown ether ligands.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 08, 1999
- Accession Number
- ADA360904
Entities
People
- Jerald S. Bradshaw
- Krzysztof E. Krakowiak
- Paul B. Savage
- Reed Izatt
- Zhaoxia Yang
Organizations
- Brigham Young University