Emergency Interventions After Severe Traumatic Brain Injury in Rats: Effect on Neuropatholgy and Functional Outcome.

Abstract

In our application, we highlighted the fact that traumatic brain injury (TBI) is an important contributor to combat casualty morbidity and mortality. We also stated that although progress has been made in the development of rodent models of TBI (such as the controlled cortical impact (CCI) model), most of the studies with these models have focused on molecular mechanisms of damage. Because there has been a paucity of application of practical emergency interventions in TBI models, we felt that it was important to address this deficiency and that this approach could have important implications for field and emergency management of both soldiers and civilians with severe TBI.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1999
Accession Number
ADA360938

Entities

People

  • Patrick M. Kochanek

Organizations

  • University of Pittsburgh

Tags

DTIC Thesaurus Topics

  • Brain
  • Brain Injuries
  • Craniocerebral Trauma
  • Health Services
  • Medical Personnel
  • Patient Care
  • Wounds And Injuries

Readers

  • Military History / Militaries and War Studies
  • Molecular and Cellular Biology
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.