Inverse Protein Folding.

Abstract

We have developed Geocore, a computer algorithm that aims to predict the 3D structures of foldable polymers from their monomer sequences. Our first work was on foundations in simplified models, and-most recently we have completed tests in which we found the method is successful in 18 peptides and small proteins. Our continuing efforts will be to speed it up and extend it to larger proteins.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 31, 1998
Accession Number
ADA361002

Entities

People

  • Ken A. Dill

Organizations

  • University of California, San Francisco

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Abstracts
  • Algorithms
  • Amino Acids
  • California
  • Classification
  • Computers
  • Information Operations
  • Military Research
  • Molecules
  • Monitoring
  • Polymers
  • Security
  • Sequences
  • Standards
  • Universities

Fields of Study

  • Computer science

Readers

  • Computational Modeling and Simulation
  • Molecular and Cellular Biochemistry
  • Nanocomposite Materials Science