Studies for the Prevention and Treatment of Malaria, Leishmania, and Other Emerging Infectious Diseases in Brazil

Abstract

Visceral leishmaniasis is an infection of the reticuloendothelial system caused by a protozoan of the Leishmania donovani complex. The lack of orally effective agents for visceral leishmaniasis prompted the clinical development of WR6026, a primaquine analog found to be highly active in animal testing. This study was an open-label, dose-escalating trial of WR6026 in the treatment of visceral leishmaniasis caused by L. chagasi.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1999
Accession Number
ADA364936

Entities

People

  • Reynaldo Dietze

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Blood
  • Diseases And Disorders
  • Infection
  • Infectious Diseases
  • Infectious Skin Diseases
  • Kidney Diseases
  • Laboratory Animals
  • Leishmania
  • Leishmaniasis
  • Malaria
  • Materials
  • Parasites
  • Parasitic Diseases
  • Side Effects
  • Toxicity

Fields of Study

  • Medicine

Readers

  • Parasitology and Pharmacology of Malaria.