Development of a Transgenic Model to Assess Bioavailable Genotoxicity in Sediments

Abstract

This technical note describes the rationale for using transgenic animal models to assess the potential genotoxicity of sediments, the benefits that can be obtained using such models versus currently used methods, the nature of the transgenic model, and the modification of an existing transgenic construct being used to develop a mutation model based on a polychaete worm at the U.S. Army Engineer Research and Development Center (ERDC). The research described in this technical note was conducted with support from the U.S. Army Engineer Long-Term Effects of Dredging Operations (LEDO) Program.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1999
Accession Number
ADA365642

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  • Aquatic Ecology
  • Breast cancer cell signaling and growth regulation.
  • Coastal and Marine Engineering/Sediment Transport/Hydraulic Engineering