Establishment of the Fox Chase Network Breast Cancer Risk Registry.

Abstract

The wealth of research regarding the complex interaction of the genetic, biologic and environmental factors associated with breast carcinogenesis offers promise towards better understanding of breast cancer. The progress in molecular genetics provides us with opportunities to expand our knowledge about modifiable causes of breast cancer. The development of the Fox Chase Cancer Center Breast Cancer Risk Registry was proposed to facilitate research in the epidemiologic and genetic predictors of disease and permitted evaluation of the effectiveness of new risk counseling, surveillance and prevention strategies. Staff training, sharing resources and administrative support were critical components to assist the community hospital to develop a high-risk program. Formal and on-going inservice training in cancer genetics, breast cancer risk and genetic educational resources, telephone consultation, DNA blood collection procedures, and continuous monitoring were necessary for implementation and coordination of a community-based risk registry. The establishment of an Advisory Panel helped address additional issues of informed consent, reimbursement, and community-based counseling strategies. This project demonstrates that with appropriate resources and support, it is feasible to establish a registry for individuals at high risk for breast cancer and further our understanding of the genetic and epidemiologic basis of the disease.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1998
Accession Number
ADA366585

Entities

People

  • Mary B. Daly

Organizations

  • Fox Chase Cancer Center

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Databases
  • Diseases And Disorders
  • Education
  • Ethnic Groups
  • Families (Human)
  • Genetic Testing
  • Genetics
  • Health Care
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Public Health
  • Risk Analysis
  • Training

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Medical or Health Care Field.
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology