Transition of Assay Techniques Developed by U.S. Army Medical Research Institute of Chemical Defense to the Medical Research and Evaluation Facility.

Abstract

"The Transition of Assay Techniques Developed by USAMRICD to the MREF" was performed under Contract DAMD 17-89-C-9050. The task is composed of the validation of three of the methods reported in Technical Bulletin (TB MED 296), entitled "Assay Techniques for Detection of Exposure to Sulfur Mustard, Cholinesterase Inhibitors, Sarin, Soman, OF, and Cyanide." The three selected methods are: Chapter 2, Verification of Sulfur Mustard Exposure - Measuring Thiodiglycol in Urine by Oas Chromatograph/Mass Spectrometer Chapter 3, Verification of Nerve Agent Exposure - Monitoring Blood Cholinesterase Activity with the Test/Mate(trademark) OP Kit Chapter 4, Verification of Nerve Agent Exposure - Measuring Alkylmethyiphosphonic Acids in Urine By Oas Chromatograph/Mass Spectrometer The following report documents the work conducted to transfer the methods to Battelle and the results of Battelle's method validation process. A brief summary of each method is provided below.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1999
Accession Number
ADA366588

Entities

People

  • Carl T. Olson
  • Thomas Dreier

Organizations

  • Battelle Memorial Institute

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Acetylcholinesterases
  • Chemical Synthesis
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemistry
  • Fluids
  • Health Services
  • Liquid Chromatography
  • Mass Spectrometers
  • Mass Spectrometry
  • Measurement
  • Medical Personnel
  • Nerve Agents
  • Organic Chemistry
  • Spectrometry
  • Test And Evaluation

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Neurotoxicology
  • Technical Research and Report Writing.