Vasopressin Gene-Related Products in the Management of Breast Cancer

Abstract

The goal of this project has been to improve the detection and treatment of breast cancer by characterizing vasopressin (VP) gene expression by this disease and determining the nature and role of products generated through this expression. The VP gene is expressed by seemingly all breast cancers and by all DCIS, and this information coupled with an absence of VP gene-related products from fibrocystic disease potentially provides us with a new diagnostic test for distinguishing both breast cancer and DCIS from atypical hyperplasia. Partial structures for these proteins have been determined, and Abs against against them have been generated.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1998
Accession Number
ADA366612

Entities

People

  • William G. North

Organizations

  • Dartmouth College

Tags

DTIC Thesaurus Topics

  • Brain
  • Breast Cancer
  • Carcinoma
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Lymphocytes
  • Medical Personnel
  • Organic Chemistry

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular Biology and Genetics
  • Systems Analysis and Design