Characterization of the Heregulin-Stimulated Activation of the Neu/ErB2 Tyrosine Kinese and Its Involvement in Breast Cancer.

Abstract

The studies outlined in the original proposal were aimed at determining the molecular basis underlying the actions of the Neu/ErbB2 tyrosine kinase and its involvement in the development and progression of breast cancer. Within this section of the final report (for the period July 15, 1994-July 15, 1998), I will discuss the background of the research problem (within the context of previous work performed by our laboratory and other laboratories), the purpose of the proposed research and the methods of approach that have been used.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1998
Accession Number
ADA366905

Entities

People

  • Richard A. Cerione

Organizations

  • Cornell University

Tags

DTIC Thesaurus Topics

  • Biomedical And Dental Materials
  • Breast Cancer
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Cytoskeleton
  • Fungi
  • Medical Personnel
  • Proteins

Readers

  • Breast cancer cell signaling and growth regulation.
  • Public Financial Management and Budgeting
  • Systems Analysis and Design