The Regulation and Function of Nuclear Receptor Corepressor SMRT in Human Breast Cancer Cells

Abstract

I will investigate the expression of SMRT in various human breast cancer cell lines and determine if retinoic acid, estrogen, and/or 4HT treatment are involved in the regulation of SMRT RNA/protein levels. This data will be compared to the levels of RAR and ER in each cell line.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1999
Accession Number
ADA367378

Entities

People

  • Christopher J. Leo

Organizations

  • University of Massachusetts

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acids
  • Biomedical Research
  • Breast Cancer
  • Cell Line
  • Cells
  • Chemistry
  • Estrogens
  • Hormones
  • Laboratory Animals
  • Law
  • Materials
  • Neoplasms
  • Proteins
  • Recombinant Dna
  • Regulations
  • Retinoic Acids

Readers

  • Breast cancer cell signaling and growth regulation.