Breast Images with Diffusing Light Waves
Abstract
The goal of our proposed work was to improve the breast tumor diagnostic capabilities of optical spectroscopy and imaging based on diffusing near infrared light. We introduced new theoretical methodologies for image reconstruction within the human breast, and planned to develop these theoretical approaches further, and test these approaches experimentally. The primary benefit derivable from these ideas is improved breast image fidelity, which in turn, would enable clinicians to fully exploit the new spectroscopic and scattering contrast mechanisms available with the optical method for increased tumor sensitivity and specificity. Since submission of this proposal we have experimentally demonstrated the theoretical ideas underlying the near-field Fast Fourier Transform approach. These experiments produced two-dimensional projection images of thin objects embedded in infinite media. The apparatus however, was not well suited for realistic parallel plate soft breast compression geometries, so during the last year we have completed the construction of an instrument that is far better suited for these more realistic studies. We have - also explored various theoretical issues including the effects of imaging filters on the reconstructions, and the potential for three-dimensional reconstruction.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1998
- Accession Number
- ADA368342
Entities
People
- Arjun Yodh
Organizations
- University of Pennsylvania