Impact of BRCA 1/2 Testing on Marital Relationships.

Abstract

The present study is a prospective examination of the impact of genetic testing for breast-ovarian cancer susceptibility on marital relationships and the quality of life of husbands. Participants are women (age 18 and older) who are members of families in which a disease conferring mutation has been identified and their spouses. Interviews of husbands and wives are completed by telephone prior to receiving test results, as well as 1-, 6-, and 12-months after test disclosure. The preliminary data showed that wives (n=49) were more likely to use avoidance, have intrusive thoughts, and experience psychological distress compared to husbands (n=35). Wives also rated higher marital satisfaction. The husbands scored lower at baseline on four of the measures of interest (the presence of intrusive thoughts, general psychological distress, state anxiety, and marital adjustment) than at 1-month follow-up (n=6). The results of the preliminary analysis suggest that husbands may experience less psychological distress than wives at the baseline assessment (pre-mutation disclosure). However, the level of distress may increase for the husbands within one month of learning of the wife's mutation status. Further analysis when more disclosures have been completed will elucidate the association between mutation status outcome and these psychological measures.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1999
Accession Number
ADA368468

Entities

People

  • Sharon Manne

Organizations

  • Fox Chase Cancer Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Data Analysis
  • Diseases And Disorders
  • Education
  • Families (Human)
  • Genes
  • Genetic Phenomena
  • Genetic Structures
  • Genetic Testing
  • Genetics
  • Health Services
  • Institutional Review Board
  • Materials
  • Medical Genetics
  • Medical Personnel
  • Surveys

Fields of Study

  • Psychology

Readers

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  • Molecular and genetic basis of cancer.
  • Organizational Psychology.

Technology Areas

  • Biotechnology