Synthesis and Aggregate Study of Bisphenol-Containing Diaza- 18-Crown-6 Ligands.

Abstract

Bisphenol-containing diaza-18-crown-6 ligands (1-16) were synthesized as potential membrane-forming amphiphiles via the one-pot Mannich reaction. Sonication of the crude products in a small amount of MeOH followed by filtration and drying proved to be an efficient method of purifying nearly all compounds. Compounds 8 and 9 were selected for assay as amphiphiles. Compared to simple, alkylated diazacrown ethers, the stability of the amphisomes formed from these monomers is lower possibly because intramolecular hydrogen bonding prevents formation of intermolecular hydrogen bonds.

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Document Details

Document Type
Technical Report
Publication Date
Sep 30, 1999
Accession Number
ADA368629

Entities

People

  • Jerald S. Bradshaw
  • Krzysztofe E. Krakowiak
  • Ning Su
  • Paul B. Savage
  • Reed M. Izaft

Organizations

  • Brigham Young University

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  • Abstracts
  • Biochemistry
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  • Crown Ethers
  • Electron Microscopy
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  • Ethers
  • Filtration
  • Hydrogen
  • Hydrogen Bonds
  • Light Scattering
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Fields of Study

  • Chemistry

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  • Analytical Chemistry
  • Organic Chemistry
  • Polymer Science and Technology