Services to Operate a Red Blood Cell Storage Laboratory

Abstract

The Bionetics Corporation staffed and maintained laboratories to support red blood cell preservation research for the Blood Research Detachment, Walter Reed Army Institute of Research, initially at 1413 Research Blvd., Rockville, MD 20850 and, after relocation, at Building 504, Walter Reed Forest Glen Annex, Silver Spring, MD 20910. Contract staff completed three in vitro trials. The first trial evaluated an investigational system for processing frozen red cells which would extend the post-thaw shelf life from 1 day to 15 days; the second compared red cells stored in a polyvinyl chloride (PVC) versus non-PVC bags and the third tested a blood sterilization process. A clinical trial, which measured the 24 hour post-transfusion survival of autologous red cells prepared in the investigational system for processing frozen red cells, was nearing completion. Preliminary results indicate fully acceptable survival after 15 days post-thaw storage. One manuscript describing research completed during the period of the previous report was published and two additional manuscripts are in press. The Bionetics Corporation advanced the Blood Research Detachment's mission.

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Document Details

Document Type
Technical Report
Publication Date
Oct 20, 1999
Accession Number
ADA370168

Entities

People

  • Lloyd Lippert

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical And Dental Materials
  • Biomedical Research
  • Blood
  • Blood Cells
  • Blood Donors
  • Blood Transfusions
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Clinical Trials
  • Contracts
  • Institutional Review Board
  • Leukocytes
  • Materials
  • Measurement
  • Medical Personnel
  • Shelf Life

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  • Technical Research and Report Writing.