Attenuation of Brain Hyperbaric Oxygen Toxicity of Fasting is Not Related to Ketosis

Abstract

The objective of this study was to determine if protection from HBO2 seizures by acute, short fasting is related to the ketosis or to the mild hypoglycemia resulting from this treatment, or to both. For this purpose, blood glucose and ketone levels were manipulated in the fed and fasted rats by injection of glucose or a ketone precursor, 1,3- butanediol (BD), and the latency to seizures was recorded.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1999
Accession Number
ADA370331

Entities

People

  • A. L. Harabin
  • J. C. Braisted
  • M. Chavko

Organizations

  • Naval Medical Research Center

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Body Weight
  • Brain
  • Central Nervous System
  • Electrodes
  • Electroencephalography
  • Food Deprivation
  • Free Radicals
  • High Pressure
  • Ketones
  • Laboratory Animals
  • Navy
  • Nervous System
  • Nutrition Disorders
  • Partial Pressure
  • Seizures

Readers

  • Marine Mammal Biology
  • Molecular and Cellular Biology
  • Toxicology/Environmental Toxicology