Computer-Aided Classification of Malignant and Benign Lesions on Mammograms

Abstract

The purpose of this project is to develop computerized classification methods for mammographic abnormalities which will aid radiologists in deciding whether a patient should be biopsied. The regions of interest (ROIs) will be identified by radiologists, and the features to be used in classification will be computer-extracted image features. In the third year of our project, we developed a segmentation method for delineating boundaries of mammographic masses. New morphological features were extracted from these boundaries. The accuracy of segmentation and the discrimination ability of the extracted morphological features were demonstrated on a data set of 249 biopsy-proven masses. To demonstrate the generalizability of our classification method, a classifier was trained on 301 masses and was tested on 91 independent masses. The classification accuracy on the independent test set (Az=O.82) was close to that of an experienced breast radiologist (Az=O.88). Morphological features were also extracted for classification of microcalcifications. Their classification accuracy was evaluated on a data set of 145 biopsy proven microcalcifications. The combination of texture and morphological feature spaces for classification of microcalcifications as malignant or benign was also investigated.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 01, 1999
Accession Number
ADA371249

Entities

People

  • Berkman Sahiner

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Accuracy
  • Algorithms
  • Artificial Intelligence
  • Breast Cancer
  • Computer Vision
  • Computers
  • Data Science
  • Data Sets
  • Databases
  • Information Processing
  • Information Science
  • Machine Learning
  • Medical Personnel
  • Neoplasms
  • Neural Networks
  • Pattern Recognition
  • Test Sets

Fields of Study

  • Medicine

Readers

  • Neural Network Machine Learning.
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Space