MEMS-Based Microanalytical System for Dielectrophoresis Studies of Biological Macromolecules

Abstract

This thesis describes a body of work specifically addressing the design and fabrication of a MEMS-based microanalytical system capable of studying the dielectrophoresis of biological macromolecules such as DNA and bovine serum albumin (BSA). Through a process of discovery that involved extensive theoretical and literature based analysis coupled with laboratory validation and extension of current dielectrophoresis knowledge, it was concluded that DNA studied in this research exhibited both negative and positive dielectrophoresis depending upon the frequency of the applied electric field. Such knowledge may lead to the application of dielectrophoresis separation techniques for DNA.

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Document Details

Document Type
Technical Report
Publication Date
Jun 15, 2000
Accession Number
ADA378734

Entities

People

  • Shane M. Crippen

Organizations

  • Air Force Institute of Technology

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Charge Carriers
  • Chemical Reactions
  • Chemistry
  • Dielectric Permittivity
  • Dielectric Properties
  • Electrical Engineering
  • Fabrication
  • Failure Mode And Effect Analysis
  • Fluid Flow
  • Macromolecules
  • Manufacturing
  • Materials Science
  • Measurement
  • Mechanics
  • Molecules
  • Soft Lithography
  • Voltage

Fields of Study

  • Chemistry

Readers

  • Geochemistry
  • Immunology
  • Theoretical Analysis.