Dermal Absorption of Chemicals From Evaporating Vehicle Mixtures.

Abstract

Unfortunately, only year Ol of this project was funded. Initial work on the project progressed slower than schedule due to delays in finding a graduate student to work on the project and in delivery of key instruments (i.e., the gas chromatograph and diffusion cell console). Consequently, work continued beyond the end of Year Ol (November 14, 1998) until April 30, 1999 under a no-cost extension. Significant progress has been made towards the principal research objective of the project. As originally proposed, this 3-year study would have included experimental measurements (i) skin-partition coefficients and (ii) dermal absorption from vapors, occluded vehicles and non-occluded volatile vehicles), combined with mathematical models for interpreting and extrapolating the experimental results to other chemicals. During the first and only year of this project, many experimental measurements were completed, and, and initial mathematical models were developed.

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Document Details

Document Type
Technical Report
Publication Date
Apr 30, 1999
Accession Number
ADA379460

Entities

People

  • Annette L. Bunge

Organizations

  • Colorado School of Mines

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Absorption
  • Aqueous Solutions
  • Biological Sciences
  • Chemical Industry
  • Chromatographs
  • Coefficients
  • Data Analysis
  • Diffusion
  • Digestive System Processes
  • Environmental Protection
  • Epidermis
  • Health
  • Mathematical Models
  • Measurement
  • Models
  • Risk
  • Risk Analysis

Readers

  • Analytical Chemistry
  • Clinical Trial Research.
  • Computational Modeling and Simulation