Genotoxicity Testing in Sediments: Progress in Developing a Transgenic Polychaete Model

Abstract

This technical note describes progress made during calendar year 1999 in the development at the U.S. Army Engineer Research and Development Center (ERDC) of a transgenic marine polychaete worm for testing genotoxicity of sediments. In keeping with the intent of previous communications, this technical note contains protocols for laboratory procedures to aid other researchers who may be similarly engaged in the development of transgenic invertebrate models for research or testing purposes. Protocols are provided for cryopreservation of polychaete sperm and for transgene insertion using electroporation combined with osmotic shock.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2000
Accession Number
ADA379487

Entities

People

  • Laura S. Inouye
  • Victor A. Mcfarland

Tags

DTIC Thesaurus Topics

  • Calcium Compounds
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Ecotoxicology
  • Fish
  • Genotoxicity
  • Indicator Dyes
  • Laboratory Procedures
  • Liquid Phases
  • Liquids
  • Materials
  • Molecular Biology
  • Phase
  • Saline Solution
  • Square Waves
  • Toxicity

Readers

  • Aquatic Ecology
  • Immunology
  • Technical Research and Report Writing.